Efeito do enxerto de tecido conjuntivo sobre a estabilidade dos tecidos moles e os desfechos estéticos peri-implantares: uma revisão integrativa
DOI:
https://doi.org/10.62331/2965-758X.v4.2026.89Palavras-chave:
Implantes dentários, Transplante de tecidos, Transplante autólogo, Mucosa bucal, Estética dentáriaResumo
A estabilidade dos tecidos moles peri-implantares é um fator determinante para o sucesso estético e funcional das reabilitações com implantes dentários. O enxerto de tecido conjuntivo (ETC) tem sido amplamente empregado para aumentar a espessura desses tecidos e favorecer a previsibilidade dos resultados clínicos. O presente estudo teve como objetivo analisar as evidências científicas sobre os efeitos do ETC na estabilidade dos tecidos moles e nos desfechos estéticos peri-implantares. Trata-se de uma revisão integrativa da literatura, realizada nas bases PubMed/MEDLINE, LILACS e Cochrane Library. Foram incluídos ensaios clínicos randomizados, ensaio clínico multicêntrico randomizado, revisão sistemática e meta-análise publicados entre 2025 e 2026. A busca identificou 330 registros, dos quais 5 estudos atenderam aos critérios de elegibilidade. Os estudos demonstraram que o ETC promove aumento da espessura dos tecidos moles peri-implantares e apresenta resultados clínicos favoráveis, embora matrizes colágenas também tenham demonstrado desempenho satisfatório em diferentes desfechos. Conclui-se que o ETC constitui uma abordagem eficaz e previsível para otimizar a estabilidade dos tecidos moles e os desfechos estéticos peri-implantares, permanece como uma das principais abordagens para aumento dos tecidos moles peri-implantares. Entretanto, novos estudos com acompanhamento em longo prazo são necessários para fortalecer as evidências disponíveis.
Referências
Moussa H, Nasri W, Gargouri R, Bouslema A. Management of soft tissue defects around single implants: a systematic review of the literature. Clin Exp Dent Res. 2024; 10(6):e70003. https://doi.org/10.1002/cre2.70003
Agarwal S, Sachdev SS, Mistry LN, Agrawal S, Deshpande S, Sharma V, et al. Soft tissue management in implant dentistry: a comprehensive review. Cureus. 2025; 17(2):e79557. https://doi.org/10.7759/cureus.79557
Zucchelli G, Tavelli L, McGuire MK, Rasperini G, Feinberg SE, Wang HL, et al. Autogenous soft tissue grafting for periodontal and peri-implant plastic surgical reconstruction. J Periodontol. 2020; 91:9-16. https://doi.org/10.1002/JPER.19-0350
Tavelli L, Barootchi S, Avila-Ortiz G, Urban IA, Giannobile WV, Wang HL. Peri-implant soft tissue phenotype modification and its impact on peri-implant health: a systematic review and network meta-analysis. J Periodontol. 2021; 92:21-44. https://doi.org/10.1002/JPER.19-0716
Liu Z, Li C, Liu Y, Zeng J, Chu H, Chen P, et al. The clinical significance and application of the peri-implant phenotype in dental implant surgery: a narrative review. Ann Transl Med. 2023; 11(10):351. https://doi.org/10.21037/atm-23-1752
Rosa LOR, Fabris AL da S. Enxerto de tecido conjuntivo associado a implantes na zona estética: uma revisão narrativa. Biosciences and Health. 2025; 3:1-7. https://doi.org/10.62331/2965-758X.v3.2025.67
Atieh MA, Alsabeeha NHM. Soft tissue changes after connective tissue grafts around immediately placed and restored dental implants in the esthetic zone: a systematic review and meta-analysis. J Esthet Restor Dent. 2020 ;32(3):280-290. https://doi.org/10.1111/jerd.12538
Durante-Lacambra R, Taheri RB, Leco-Berrocal MI, López-Carriches C. Influence of connective tissue grafts on implants in the aesthetic area: a systematic review. Are connective grafts essential? J Clin Exp Dent. 2024; 16(6):e772-e777. https://doi.org/10.4317/jced.61668
Rondone EM, Leitão-Almeida B, Pereira MS, Fernandes GVO, Borges T. The use of tissue grafts associated with immediate implant placement to achieve better peri-implant stability and efficacy: a systematic review and meta-analysis. J Clin Med. 2024; 13(3):821. https://doi.org/10.3390/jcm13030821
Zafar F, Riaz M, Ahmed R, Kumar R. Soft-tissue augmentation for increasing keratinized tissue around dental implants: a systematic review. J Indian Soc Periodontol. 2024; 28(4):417-426. https://doi.org/10.4103/jisp.jisp_429_23
Sabri H, Tavelli L, Sheikh AT, Kalani K, Huang K, Zimmer JM, et al. Significance of peri-implant keratinised mucosa on implant health: an umbrella systematic review with evidence mapping and quantitative meta-meta-analysis. Int J Oral Implantol. 2025; 18:13-30. Disponível em: https://pubmed.ncbi.nlm.nih.gov/40047360/
Zhang Z, Zhang Z, Wang P, Zheng Y, Wang Z, Wang Z. The relationship between adequate keratinized mucosa and peri-implant disease: a systematic review and meta-analysis. BMC Oral Health. 2025; 25:345. https://doi.org/10.1186/s12903-025-05680-5
Seyssens L, De Lat L, Cosyn J. Immediate implant placement with or without connective tissue graft: a systematic review and meta-analysis. J Clin Periodontol. 2021; 48(2):284-301. https://doi.org/10.1111/jcpe.13397
Torra-Moneny M, Mauri-Obradors E, Egido-Moreno S, Valls-Roca-Umbert J, Marí-Roig A, López-López J. Association of connective tissue grafts in immediate implants: systematic review and meta-analysis. Dent J. 2024; 12(6):183. https://doi.org/10.3390/dj12060183
Whittemore R, Knafl K. The integrative review: updated methodology. J Adv Nurs. 2005; 52(5):546-553. https://doi.org/10.1111/j.1365-2648.2005.03621.x
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021; 372:n71. https://doi.org/10.1136/bmj.n71
Ashurko I, Tarasenko S, Magdalyanova M, Balyasin M, Galyas A, Kazumyan S, et al. 3D-analysis of peri-implant soft tissue gain with collagen matrix and connective tissue graft: a randomized control trial. Clin Implant Dent Relat Res. 2025; 27(2):e70043. https://doi.org/10.1111/cid.70043
Azadi A, Rezaei F, Yazdani A, Hejazi K, Moallem Savasari A, Amid R, et al. Hard and soft tissue alterations after the application of different soft tissue grafting materials during immediate dental implant placement: a systematic review and Bayesian network meta-analysis. BMC Oral Health. 2025; 25:183. https://doi.org/10.1186/s12903-025-05461-0
Ferrarotti F, Baima G, Mohammadi G, Carboncini C, Romano F, Aimetti M. Peri-implant soft tissue increase at small buccal bone dehiscences with either volume-stable collagen matrix or connective tissue graft: a randomized controlled trial. Clin Oral Implants Res. 2025; 36(7):846-858. https://doi.org/10.1111/clr.14430
Cairo F, Rupe C, Cavalcanti R, Landi L, Rupe A, Sforza NM, et al. Cross-linked volume-stable collagen matrix versus connective tissue graft for soft tissue augmentation at implant site. a non-inferiority, multicenter randomized clinical Trial. Clin Oral Implants Res. 2026; 37:45-56. https://doi.org/10.1111/clr.70050
Abdelmaged HA, Moustafa AA, Khalil AA. Modified vascularized interpositional periosteal connective tissue graft versus xenogeneic collagen matrix for soft tissue augmentation around implant in esthetic zone (a comparative study). BMC Oral Health. 2025; 25:1932. https://doi.org/10.1186/s12903-025-07345-9
Tarlao AC, Arruda FJS de, Fernandes SL, Miranda AGV, Sousa UR de. Reabilitação do elemento 37 com implante e enxerto de tecido conjuntivo: relato de caso clínico e abordagem interdisciplinar. Biosciences and Health. 2025; 3:1-10. https://doi.org/10.62331/2965-758X.v3.2025.74
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Copyright (c) 2026 Euclides Tozzi Pelarin, Farid Jamil Silva de Arruda
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